Department of Medical Polymers

The department was created in 1965. Since 1995, Head of the Department of Biological Sciences Dr. NA Galatenko. Since 1998, the department was called – Department of polymers of medical appointment.

The main scientific direction of the department: mechanisms of interaction urethanecontaining polymers with macromolecules of biologically active compounds.

The department prepared 2 doctors and 16 candidates. Scientific achievements outlined in eight books, 203 scientific articles, 35 are protected by patents.

The department awarded the State Prize of Ukraine Academy of Science and Technology, the International Prize of the Academy of Sciences of the USSR and Czechoslovakia, awarded medals VDNH USSR and others.
The main achievements of depertment

The theoretical principles of hydrophilic polymer systems for directional transport of drugs into the body.

The proposed synthesis and chemical modification of urethane polymers, biologically active compounds and studied their potential role as medical polymers.

Scientifically proved methods for creating hydrophilic and hydrophobic polymer matrix based on polyurethanes, poly-N-vinilpirrolidonu and hydrogels as carriers of endogenous and exogenous drugs.

The mechanism of tumor reversion under local influence inductors of differentiation tumor tissue.

Established mechanisms of action of bioactive ceramics as part polyurethanes processes osteosynthesis bone.

By the results of basic research developed:

1. antitumor glue “Levkin” with immunomodulatory properties for treating pathologies of bone and soft tissues;
2. burn high-performance coatings and medical plasters to treat wounds and burns that stimulate tissue regeneration processes and a broad spectrum of antimicrobial action;
3. biologically active compositions with bioactive ceramics to remove bone defects and for the manufacture of metal-plastic endoprosthesis;
4. Antiseptic hydrophilic materials for catheters and drainage-band for abdominal surgery;
5. Polymer materials for the manufacture of shells hydrophilic endoprosthesis for plastics breasts.

List of selected works department:

1. R.Rozhnova, N.Galatenko, T.Zakashun, T.Mnyshenko // Biochemical Characteristic of the Reaction of Connective Tissue to Bioactive Polyurethane Implants with Hydroxyapatite. – Dopovidi NANU, No.5, 1998, p.158-161
2. T.Mnyshenko, T.Zakashun, G.Galatenko // Prolonged-Therapy Polyurethane/Bioceramic Composite for Bone Tissue Plastics. – Dopovidi NANU.- No.3.- 1999.-p.160-162.
3. R.Rozhnova, N.Galatenko // In-vivo Investigation of the Submicroscopic and Phase-Crystalline Structures of Polyurethane/Hydroxyapatite Composites. – Dopovidi NANU.- No.4.- 1999.-p.158-161.
4. R.Rozhnova, N.Galatenko // Biologically active polymeric implants for plastic bone tissue .- Journal of the Inter. Federat. for Medical & Biological Engineering ,Tallinn, Estonia, v.37, Suppl. 1, p.185-186.
5. G.Galatenko, N.Zbanatskaya , R. Rozhnova, Y.Levenec, Konovalenko V.// A Polyurethane Composite for Bone Tissue Plastics.- Patent of Ukraine Priority No. 36224A, 16.04.2001
6. L. Zhernova, N. Galatenko, V. Khranovskiy. A // Study on the Biostability of Fluorinated Polyurethanes.- Kompozitsionnyye Materialy IkhVS NANU. V. 22, No.1, 2000, p.26-30.
7. R. Rozhnova, V. Shylov, N. Galatenko.// A Study on the Structural Morphology of Prolonged-Therapy Bioactive Implants.- Kompozitsionnyye Materialy IkhVS NANU. V.22, No.2, 2000, p.146-150.
8. O. Savchuk, N. Zbanatskaya, L. Nechayeva, N. Galatenko. // A Composite based on Stiol-F Cement and Amisone: the Development and Physicochemical Properties.- Dopovidi NANU, No.12, 2000, p.191-194.
9. A. Fainleib, T. Shantalii, O Klochok, N. Galatenko.// Synthesis and Some Properties of Poly(bisphenol A0-cyanurate Modified with Oligoethers. -Kompozitsionnyye Materialy IkhVS NANU. v.23, No.1, 2001, p.14-19.
10. A. Pochinok, K. Chernoshtan, G. Lougovskaya, N. Galatenko. // Polymer-Based Transdermal Therapeutic Systems Containing Anapriline. -Liky, No.5, 2001, p.67-70.
11. R. Rozhnova, V. Bondarchuk, E. Savitskaya, V. Popov, N. Galatenko. // Bone Repair with a Highly Hydroxiapatite-Filled Polymer Composite.- Vrachebnoye Delo, No.1, 2002, p.107-109.
12. R. Rozhnova, N. Galatenko.// Peculiarities of Medico-biological Control of Polymeric Materials Having a Therapeutic Effect.- Problemy Toksikologii, No.2, 2002, p.64-68.
13. O Klochok, N. Galatenko, V.Gritsenko , E.Savitskaya // Production of Modified Polycyanurates for Use as Durable Implants.- Dopovidi NANU, No.8, 2001, p.158-160..
14. Rozhnova R., Galatenko N., Konovalenko V. // Anticarcinogenic polymeric composition with immunomodulator for tissue plastic.- IFMBE Proceeding MEDICON 2001 Mediterranean IX Conference on Medical and Bioligical Engineering and Computing, Pula, Croatia, June 12-15, 2001, p. 824-827.
15. M.Grigorieva, I.Gladir, N.Galatenko // The Polyuretane-Drug Composites: Synthesis, Properties and Kinetic Models.- J.of Bioactive and Compatible Polymers, vol.16, 2001, p.161-168.
16. M.Grigorieva, I.Gladir , N.Galatenko //Bioactive Polyuretane Carriers.- Conference Papers “Advances in Plastics Technology “, Katovice, Polland, 18-20 Sept., 2001, p.241-247.
17. Zhernovaya L., Lougovskaya G.,Pochinok A., Grigorieva M., Galatenko N., Nechayeva L. // Macromolecular Therapeutic Systems Containing Cephalosporine Antibiotics. .- Dopovidi NANU, No.10, 2001, p.139-144.
18. Rozhnova R., Kebuladze I.,Galatenko N.// Bioactive Polyurethane Implants with Hydroxyapatite.- .Key Engineering Materials, Bioceramics, 13, 2001, p.693-696.
19. Zhernovaya L., Lougovskaya G., Rudenko A., Savitskaya E., Tarasov T., Galatenko N. // Biocompatible Polyurethane Composites with an Antimicrobial Activity.- Dopovidi NANU, No.5, 2002, p.185-189.
20. O.Savchuk, R.Rozhnova, L. Nechayeva, Y.Levenec, V. Khranovsky, N.Galatenko // Silica-inomeric material with prolonged medical action for stomatology.- Kompozitsionnyye Materialy IkhVS NANU. V. 24, No.1, 2002, p.48-51.
21. Klochok E., Rozhnova R., Galatenko N. // Synthesis and Study of the Physicochemical Properties of Polyurethane/Amisone Composites.- Dopovidi NANU, No.11, 2002, p.149-151.
22. Grigorieva M., Gladir I., Galatenko. N. // Cephasoline-filled Polyurethane Carriers.- Ukr.chem.journal, т.68, No 4, 2002, с.125-127.
23. G. Lougovskaya, A. Pochinok, I. Gladir, E. Karpik, I. Budilova, N. Galatenko. // Creation of a Broad-Spectrum Film Dressing for Treatment of Wounds and Burns.- Plastychna ta Rekonstruktyvna Khirurhiya, No.1, 2002, p.
24. Rozhnova R., Galatenko N. // Highly filled polymer composition by hydroxyapatite for orthopedic.- CIMIEC 2002, Forum on New Materials, Italy, Florence, 21-24 June, 2002.
25. Lugovska G.G., Pochinok A.V., Galatenko N.A. et al. Creation of film dressing material for treatment burns and wounds with wide spectrum of medical action // J. Plactic and Reconstrucive surgery.- 2003.- N 1, V.1.- P.1-427.
26. Galatenko N., Rozhnova R., Kebuladze I. et al. Study of biocompatibility of linear polyurethanes for endoprosthesis // J. Reports of NASc of Ukraine.- 2003.- N1.- P.48-5128.
27. Study of biocompatibility and biostability of fluorine-containing polyurethanes // J. Chemistry, physics and technology of coating.- 2003.- V.9.- P. 53-56.

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